MDR-TB and XDR-TB: drug resistance and treatment outcomes.

نویسندگان

  • G B Migliori
  • G Sotgiu
  • M D'Arcy Richardson
  • R Centis
  • A Facchini
  • G Guenther
  • A Spanevello
  • C Lange
چکیده

The subject is quite topical, as TB programmes and clinicians are searching for solutions to treat MDR/XDR-TB most effectively. Recently published studies and a systematic review have shown that XDR-TB is associated with higher probability of failure and death, and lower probability of treatment success than MDR-TB [2–7]. The XDR-TB-defining drugs have been studied to evaluate their role in determining successful outcomes in MDR/XDR-TB cases (XDR-TB is defined as resistance to at least isoniazid and rifampicin (MDR-TB) plus to any fluoroquinolone and at least one of three injectable antiTB drugs (amikacin, capreomycin or kanamycin) [2, 3]).

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عنوان ژورنال:
  • The European respiratory journal

دوره 34 3  شماره 

صفحات  -

تاریخ انتشار 2009